Article
An integrative approach uncovers genes with perturbed interactions in cancers
2019-08-13
Abstract excerpt
A major challenge in cancer genomics is to identify genes with functional roles in cancer and uncover their mechanisms of action. Here, we introduce a unified analytical framework that enables rapid integration of multiple sources of information in order to identify cancer-relevant genes by pinpointing those whose interaction or other functional sites are enriched in somatic mutations across tumors. Our accompanyi...
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Identifiers and source
- Literature Corpus work
- c973ce59-a8a9-5ec2-a8f0-5ce5363ef01f
- DOI
- 10.1101/733485