Article

Prominent features of the amino acid mutation landscape in cancer

2017-05-09

Abstract excerpt

<h4>ABSTRACT</h4> Cancer can be viewed as a set of different diseases with distinctions based on tissue origin, driver mutations, and genetic signatures. Accordingly, each of these distinctions have been used to classify cancer subtypes and to reveal common features. Here, we present a different analysis of cancer based on amino acid mutation signatures. Non-negative Matrix Factorization and principal component a...

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Literature Corpus work: b76841bb-615b-5d6c-8cf8-6cf6853d2090
DOI: 10.1101/136002

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