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The regulatory role of anti-sigma factor, RsbW, in <i>Clostridioides difficile</i> stress response, persistence and infection

2022-08-23

Abstract excerpt

<h4>Summary</h4> The anaerobic pathogen Clostridioides difficile , a primary cause of antibiotic-associated diarrhoea, faces a variety of stresses in the environment and in the mammalian gut. To cope with environmental stresses, it uses the alternative sigma factor B (σ B ) to modulate gene transcription, which is regulated by an anti-sigma factor, RsbW. To understand the role of RsbW in C. difficile physiolog...

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Literature Corpus work
865d0fb3-70f1-5dcb-98ea-7f131bea3349
DOI
10.1101/2022.08.22.504775
Open publication

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