Article

Estimating HLA disease associations using similarity trees

2018-09-04

Abstract excerpt

The human leukocyte antigen (HLA) is associated with many (infectious) disease outcomes. These associations are perhaps best documented for HIV-1. For example, the HLA-B*58:01 allele is associated with control of the virus, while HLA-B*18:01 is considered detrimental. In HLA disease association studies, it is often ignored that certain HLA molecules are functionally very similar to others. For instance, HLA-B*18:0...

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Literature Corpus work: c947a68f-23e9-56d5-85fe-8ce8493128d2
DOI: 10.1101/408302

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