Article
Impact of predicted HLA class I immunopeptidome on viral reservoir in a cohort of people living with HIV in Italy.
HLA - 1 Jan 2024
Rovatti Pier Edoardo, Muccini Camilla, Punta Marco, Galli Laura, Mainardi Ilaria, Ponta Giacomo, Vago Luca Aldo Edoardo, Castagna Antonella
Abstract excerpt
The class I HLA genotype has been widely recognized as a factor influencing HIV disease progression in treatment-naïve subjects. However, little is known regarding its role in HIV disease course and how it influences the size of the viral reservoir once anti-retroviral therapy (ART) is started. Here, leveraging on cutting-edge bioinformatic tools, we explored the relationship between HLA class I and the HIV...
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