Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Asymmetric linkage disequilibrium: Tools for assessing multiallelic LD.

Human immunology - 1 Mar 2016

Single Richard M, Strayer Nick, Thomson Glenys, Paunic Vanja, Albrecht Mark, Maiers Martin

Abstract excerpt

Standard measures of linkage disequilibrium (LD) provide an incomplete description of the correlation between two loci. Recently, Thomson and Single (2014) described a new asymmetric pair of LD measures (ALD) that give a more complete description of LD. The ALD measures are symmetric and equivalent to the correlation coefficient r when both loci are bi-allelic. When the numbers of alleles at the two loci differ,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Computational Biology
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to HLA Antigens

Share to Linkage Disequilibrium

Share to Software

Share to Web Browser

Source

Identifiers

PMID: 26359129
DOI: 10.1016/j.humimm.2015.09.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Asymmetric linkage disequilibrium: Tools for assessing multiallelic LD.PMID 26359129Read ↗

Conditional asymmetric linkage disequilibrium (ALD): extending the biallelic r2 measure.Semantic proximity Read ↗

An equal-tempered measure of linkage disequilibrium.Semantic proximity Read ↗

Haplotype-specific linkage disequilibrium patterns define the genetic topography of the human MHC.Semantic proximity Read ↗

Visualizing SNP statistics in the context of linkage disequilibrium using LD-Plus.Semantic proximity Read ↗

Measuring ambiguity in HLA typing methods.Semantic proximity Read ↗

A sequence-based approach demonstrates that balancing selection in classical human leukocyte antigen (HLA) loci is asymmetric.Semantic proximity Read ↗

AllelicImbalance: an R/bioconductor package for detecting, managing, and visualizing allele expression imbalance data from RNA sequencing.Semantic proximity Read ↗

Estimating HLA disease associations using similarity treesSemantic proximity Read ↗

Population structure in the MHC regionSemantic proximity Read ↗

Linkage disequilibrium maps and location databases.Semantic proximity Read ↗

Allele sharing and allelic association I: sib pair tests with increased power.Semantic proximity Read ↗

On measures of association among genetic variables.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.