Article

Cohesin forms fountains at active enhancers in <i>C. elegans</i>

2023-07-16

Abstract excerpt

Transcriptional enhancers must locate their target genes with both precision and efficiency. In mammals, this specificity is facilitated by topologically associated domains (TADs), which restrict the enhancer search space through three-dimensional genome organization. In contrast, the nematode genome lacks such TAD-based segmentation despite harboring over 30’000 sequences with chromatin signature characteristic o...

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Literature Corpus work: c93907d7-2093-5ed8-af7b-f436a7eebea9
DOI: 10.1101/2023.07.14.549011

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