Article
A yeast phenomic model for the influence of Warburg metabolism on genetic buffering of doxorubicin
2019-01-15
Abstract excerpt
<h4>Background</h4> Saccharomyces cerevisiae represses respiration in the presence of adequate glucose, mimicking the Warburg effect, termed aerobic glycolysis. We conducted yeast phenomic experiments to characterize differential doxorubicin-gene interaction, in the context of respiration vs. glycolysis. The resulting systems level biology about doxorubicin cytotoxicity, including the influence of the Warburg ef...
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Identifiers and source
- Literature Corpus work
- c90f29c0-7dda-5336-9b24-debbce20459b
- DOI
- 10.1101/517490