Article

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

2026-05-20

Abstract excerpt

<h4>Objectives</h4> Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of neuromuscular involvement. We assessed the associations of TnT and...

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Literature Corpus work: c8ea46c8-0318-54d3-9b0a-69205c55a5ac
DOI: 10.64898/2026.05.17.26353398

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