Article

Population-based Evidence for the Use of Serum Neurofilaments as Individual Diagnostic and Prognostic Biomarkers in Amyotrophic Lateral Sclerosis

2023-11-28

Abstract excerpt

<title>Abstract</title> <p> OBJECTIVE Neurofilament light (NfL) and phosphorylated heavy chains (pNfH), established as diagnostic and prognostic biomarkers in hospital-based amyotrophic lateral sclerosis (ALS) cohorts, are now surrogate markers in clinical trials. This study extends their evaluation to a population level, with the aim of advancing their full establishment and assessing the transferability of bio...

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Literature Corpus work: 3de6a800-8d81-5b29-a98c-29215e6ee722
DOI: 10.21203/rs.3.rs-3159648/v2

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