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Prognostic Clinical and Biological Markers for Amyotrophic Lateral Sclerosis Disease Progression: Validation and Implications for Clinical Trial Design and Analysis

2024-08-13

Abstract excerpt

<h4>Structured Summary</h4> <h4>Background</h4> With increasing recognition of the value of incorporating prognostic markers into amyotrophic lateral sclerosis (ALS) trial design and analysis plans, there is a pressing need to understand which among the prevailing clinical and biochemical markers have real value, and how they can be optimally used. <h4>Methods</h4> A subset of patients with ALS recruited through t...

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Literature Corpus work
dd8a8078-e888-572e-8eec-d9d1f34508c0
DOI
10.1101/2024.08.12.24311876
Open publication

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Prognostic Clinical and Biological Markers for Amyotrophic Lateral Sclerosis Disease Progression: Validation and Implications for Clinical Trial Design and AnalysisDOI 10.1101/2024.08.12.24311876
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