Article

From bats to humans: uncovering <i>ISG15</i> as a new resistance factor in type 1 diabetes

2026-04-06

Abstract excerpt

<h4>ABSTRACT</h4> Viral infections are one of the main environmental factors triggering type 1 diabetes (T1D). Pancreatic alpha cells are more resistant than beta cells to diabetogenic viruses, partially explaining their survival in T1D. Similarly, bats have enhanced viral resistance, suggesting putative convergent evolution in antiviral mechanisms. Herein, we compared global gene expression in bat fibroblasts un...

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Literature Corpus work: c8c93166-fe32-5247-afea-02e2907548d9
DOI: 10.64898/2026.04.02.713107

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