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Bat genomes illuminate adaptations to viral tolerance and disease resistance

29 Jan 2025

Abstract excerpt

Zoonoses are infectious diseases transmitted from animals to humans. Bats have been suggested to harbour more zoonotic viruses than any other mammalian order1. Infections in bats are largely asymptomatic2,3, indicating limited tissue-damaging inflammation and immunopathology. To investigate the genomic basis of disease resistance, the Bat1K project generated reference-quality genomes of ten bat species, including...

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PMID: 39880942
DOI: 10.1038/s41586-024-08471-0

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