Article

The IFN response in bat cells consists of canonical and non-canonical ISGs with unique temporal expression kinetics

2017-07-24

Abstract excerpt

Bats are reservoirs for a number of highly pathogenic zoonotic viruses, yet they remain relatively asymptomatic during infection. Whether this viral resistance is due to a unique innate immune system is unknown. An evolutionarily conserved feature of vertebrate antiviral immunity is the interferon (IFN) response, which triggers cellular defenses through interferon-stimulated gene (ISG) expression. While bats encod...

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Literature Corpus work: e8783d47-6f8c-5f81-a465-c31f2784f3d5
DOI: 10.1101/167999

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