Article

Spliced HLA bound peptides; a Black-Swan event in Immunology

2021-01-04

Abstract excerpt

Peptides that bind to and are presented on the cell surface by Human Leukocyte Antigens (HLA) molecules play a critical role in adaptive immunity. For a long time, it was believed all of the HLA bound peptides were generated through simple proteolysis of linear sequences of cellular proteins, and therefore, are templated in the genome and proteome. However, evidence for untemplated peptide ligands of HLA molecules...

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Literature Corpus work: c8680399-337a-5bc6-b281-bfd756716f4c
DOI: 10.22541/au.160976778.87618567/v1

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