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Article

Analysis of the HLA-DR peptidome from human dendritic cells reveals high affinity repertoires and nonconventional pathways of peptide generation.

Journal of leukocyte biology - 1 Jan 2017

Ciudad M Teresa, Sorvillo Nicoletta, van Alphen Floris P, Catalán Diego, Meijer Alexander B, Voorberg Jan, Jaraquemada Dolores

Abstract excerpt

Dendritic cells (DCs) are the major professional APCs of the immune system; however, their MHC-II-associated peptide repertoires have been hard to analyze, mostly because of their scarce presence in blood and tissues. In vitro matured human monocyte-derived DCs (MoDCs) are widely used as professional APCs in experimental systems. In this work, we have applied mass spectrometry to identify the HLA-DR-associated...

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PMID: 27365532
DOI: 10.1189/jlb.6HI0216-069R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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