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Article

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.

The Journal of experimental medicine - 1 Jul 1993

Chicz R M, Urban R G, Gorga J C, Vignali D A, Lane W S, Strominger J L

Abstract excerpt

Naturally processed peptides were acid extracted from immunoaffinity-purified HLA-DR2, DR3, DR4, DR7, and DR8. Using the complementary techniques of mass spectrometry and Edman microsequencing, > 200 unique peptide masses were identified from each allele, ranging from 1,200 to 4,000 daltons (10-34 residues in length), and a total of 201 peptide sequences were obtained. These peptides were derived from 66...

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Source

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Identifiers

PMID: 8315383
DOI: 10.1084/jem.178.1.27
PMCID: PMC2191090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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