Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands

12 Oct 2018

Abstract excerpt

The diversity of peptides displayed by class I human leukocyte antigen (HLA) plays an essential role in T cell immunity. The peptide repertoire is extended by various posttranslational modifications, including proteasomal splicing of peptide fragments from distinct regions of an antigen to form nongenomically templated cis-spliced sequences. Previously, it has been suggested that a fraction of the immunopeptidome...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunotherapy and Immune Responses
Share to Monoclonal and Polyclonal Antibodies Research
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30315122
DOI: 10.1126/sciimmunol.aar3947

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligandsPMID 30315122Read ↗

Spliced HLA bound peptides; a Black-Swan event in ImmunologySemantic proximity Read ↗

Elucidation of the signatures of proteasome-catalysed peptide splicingSemantic proximity Read ↗

HLA binding of self-peptides is biased towards proteins with specific molecular functionsSemantic proximity Read ↗

Elucidation of the Signatures of Proteasome-Catalyzed Peptide SplicingSemantic proximity Read ↗

Reanalysis of Immunopeptidomics Datasets Provides Mechanistic Insight into TAPBPR-Mediated Peptide Editing on HLA-A, -B and -C MoleculesSemantic proximity Read ↗

The C-terminal extension landscape of naturally presented HLA-I ligandsSemantic proximity Read ↗

Identification of the Cryptic HLA-I ImmunopeptidomeSemantic proximity Read ↗

Reanalysis of Immunopeptidomics Datasets Provides Mechanistic Insight into TAPBPR-Mediated Peptide Editing on HLA-A, -B and -C MoleculesSemantic proximity Read ↗

Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificitySemantic proximity Read ↗

Comprehensive Analysis of the Naturally Processed Peptide Repertoire: Differences between HLA-A and B in the Immunopeptidome.Semantic proximity Read ↗

Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificitySemantic proximity Read ↗

The cancer exome generated by alternative mRNA splicing dilutes predicted HLA class I epitope density.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.