Article

Elucidation of the signatures of proteasome-catalysed peptide splicing

2020-04-05

Abstract excerpt

Proteasomes catalyse the degradation of endogenous proteins into oligopeptides, but can concurrently create spliced oligopeptides through ligation of previously non-contiguous peptide fragments. Recent studies have uncovered a formerly unappreciated role for proteasome-catalysed peptide splicing (PCPS) in the generation of non-genomically templated human leukocyte antigen class I (HLA-I)-bound cis- spliced peptid...

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Literature Corpus work: df2739a5-a45a-55bf-baac-3fd46c03fc4c
DOI: 10.1101/2020.04.05.025908

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