Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

What We See, What We Do Not See, and What We Do Not Want to See in HLA Class I Immunopeptidomes

13 Jun 2020

Abstract excerpt

The identification of peptides bound to human leukocyte antigen class I (HLA-I) molecules-that is, the HLA-I immunopeptidome-is a useful tool in the hunt for epitopes suitable for vaccinations and immunotherapies. These peptides are mainly generated by proteasomes through peptide hydrolysis and peptide splicing. In this issue, Nicastri and colleagues compared different methods for the elution of HLA class...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycosylation and Glycoproteins Research
Share to Peptidase Inhibition and Analysis
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32533627
DOI: 10.1002/pmic.202000112

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

What We See, What We Do Not See, and What We Do Not Want to See in HLA Class I ImmunopeptidomesPMID 32533627Read ↗

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligandsSemantic proximity Read ↗

The Impact of the 'Mis-Peptidome' on HLA Class I-Mediated Diseases: Contribution of ERAP1 and ERAP2 and Effects on the Immune Response.Semantic proximity Read ↗

Spliced HLA bound peptides; a Black-Swan event in ImmunologySemantic proximity Read ↗

Comprehensive Analysis of the Naturally Processed Peptide Repertoire: Differences between HLA-A and B in the Immunopeptidome.Semantic proximity Read ↗

HLA-F Allele-Specific Peptide Restriction Represents an Exceptional Proteomic Footprint.Semantic proximity Read ↗

Pitfalls in HLA Ligandomics—How to Catch a Li(e)gandSemantic proximity Read ↗

Identification of the Cryptic HLA-I ImmunopeptidomeSemantic proximity Read ↗

The Choice of HLA‐Associated Peptide Enrichment and Purification Strategy Affects Peptide Yields and Creates a Bias in Detected Sequence RepertoireSemantic proximity Read ↗

The potential of plasma HLA peptides beyond neoepitopesSemantic proximity Read ↗

HLA binding of self-peptides is biased towards proteins with specific molecular functionsSemantic proximity Read ↗

ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-EpitopesSemantic proximity Read ↗

ERAP2 Increases the Abundance of a Peptide Submotif Highly Selective for the Birdshot Uveitis-Associated HLA-A29Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.