Article

Single-cell atlas of transcript usage remodelling in antiviral immune responses across human populations

2026-05-04

Abstract excerpt

Humans exhibit substantial interindividual variation in their immune responses to infection, yet the contribution of transcript usage —the relative abundance of gene isoforms— to this variation remains poorly understood. Here, we generate the first single-cell atlas of transcript usage variation during early responses to influenza A virus and SARS-CoV-2 across 160 individuals of African and European ancestry. We s...

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Literature Corpus work: c85e521e-7359-518c-8c9c-600acfbda3c3
DOI: 10.64898/2026.04.30.721889

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