Article

Direct RNA Sequencing Reveals m6A Modifications and Isoform Changes in SARS-CoV-2-Infected HEK Cells

2025-03-12

Abstract excerpt

SARS-CoV-2 infection triggers complex host responses, including alterations in RNA transcription, and modification. Understanding these changes is crucial for elucidating viral pathogenesis and identifying potential therapeutic targets. We used direct RNA sequencing to comprehensively profile the transcriptomic and epitranscriptomic landscapes of human HEK-AT cells infected with SARS-CoV-2 at 8 hours post-infectio...

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Literature Corpus work: 084818cf-09e0-53aa-bf59-acfe4384e4b5
DOI: 10.1099/acmi.0.001019.v1

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