Article

Immediate-Early Genes as Influencers in Genetic Networks and their Role in Alzheimer’s Disease

2024-03-29

Abstract excerpt

<h4>Abstract/Summary</h4> Immediate-early genes (IEGs) are a class of activity-regulated genes (ARGs) that are transiently and rapidly activated in the absence of de novo protein synthesis in response to neuronal activity. We explored the role of IEGs in genetic networks to pinpoint potential drug targets for Alzheimer’s disease (AD). Using a combination of network analysis and genome-wide association study (GWAS...

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Literature Corpus work: c7fd10c4-735b-53f4-85a8-c70f2fe68581
DOI: 10.1101/2024.03.29.586739

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