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Robust detection of oncometabolic aberrations by <sup>1</sup> H- <sup>13</sup> C heteronuclear single quantum correlation in live cells and intact tumors <i>ex-vivo</i>

2019-12-19

Abstract excerpt

Extensive efforts have been made to use non-invasive 1 H magnetic resonance (MR) spectroscopy to quantify metabolites that are diagnostic of specific disease states. Within the realm of precision oncology, these efforts have largely centered on quantifying 2-hydroxyglutarate (2-HG) in tumors harboring isocitrate dehydrogenase 1 ( IDH1 ) mutations. As many metabolites have similar chemical shifts, the resulting...

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Literature Corpus work
c6febe6d-bc02-5f7c-9ca0-d53f0cc8111e
DOI
10.1101/2019.12.18.881177
Open publication

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Robust detection of oncometabolic aberrations by <sup>1</sup> H- <sup>13</sup> C heteronuclear single quantum correlation in live cells and intact tumors <i>ex-vivo</i>DOI 10.1101/2019.12.18.881177
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