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Human forebrain organoids-based multi-omics analyses reveal PCCB's regulation on GABAergic system contributing to schizophrenia

2023-03-29

Abstract excerpt

<title>Abstract</title> <p>Identifying genes whose expression is associated with schizophrenia (SCZ) risk by transcriptome-wide association studies (TWAS) facilitates downstream experimental studies. Here, we integrated multiple published datasets of TWAS (including FUSION, PrediXcan, summary-data-based Mendelian randomization (SMR), joint-tissue imputation approach with Mendelian randomization (MR-JTI)), gene co...

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Literature Corpus work
c6be9353-46ee-5849-a90f-d9fdd9c5790d
DOI
10.21203/rs.3.rs-2674668/v1
Open publication

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Human forebrain organoids-based multi-omics analyses reveal PCCB's regulation on GABAergic system contributing to schizophreniaDOI 10.21203/rs.3.rs-2674668/v1
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