Back to search

Article

Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia.

2022-12-07

Abstract excerpt

<title>Abstract</title> <p>Schizophrenia is a neuropsychiatric disorder, caused by a combination of genetic and environmental factors. Recently, metabolomic studies based on patients’ biofluids and post-mortem brain specimens have revealed altered levels of distinct metabolites between healthy individuals and patients with schizophrenia (SCZ). However, a putative link between dysregulated metabolites and distorte...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
542997bb-ffa4-59a7-82f2-df4565cc4799
DOI
10.21203/rs.3.rs-2175912/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia.DOI 10.21203/rs.3.rs-2175912/v1
The Proteomic Architecture of Schizophrenia Cerebral Organoids Reveals Alterations in GWAS and Neuronal Development FactorsSemantic proximity
Current progress in understanding Schizophrenia using genomics and pluripotent stem cells: A Meta-analytical overviewSemantic proximity
Proteome analysis of schizophrenia brain tissueSemantic proximity
Multiomics Evaluation of Human iPSCs and iPSC-Derived NeuronsSemantic proximity
From Molecules to the Clinic: Linking Schizophrenia and Metabolic Syndrome through Sphingolipids MetabolismSemantic proximity
Integrative multiomics profiling of cortical brain organoids reveals a druggable alternative splicing program in schizophreniaSemantic proximity
Human forebrain organoids-based multi-omics analyses reveal PCCB's regulation on GABAergic system contributing to schizophreniaSemantic proximity
Multi-omic analysis of guided and unguided forebrain organoids reveal differences in cellular composition and metabolic profilesSemantic proximity
A preliminary metabolomics study of the database for biological samples of schizophrenia among Chinese ethnic minorities.Semantic proximity
Plasmalogen deficiency and purinergic stress define three metabolic axes in schizophreniaSemantic proximity
Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanismsSemantic proximity
A Multi-omics Method Enabled by Sequential Metabolomics and Proteomics for Human Pluripotent Stem Cell-derived CardiomyocytesSemantic proximity
Select a neighboring publication to make it the new centre.