Article

An Integrative Analysis Identified Schizophrenia-Associated Brain Cell Types and Gene Expression Changes

2022-08-18

Abstract excerpt

Schizophrenia (SCZ) is a severe mental disorder that may result in hallucinations, delusions, and extremely disordered thinking. How each cell type in the brain contributes to SCZ occurrence is still unclear. Here, we leveraged the human dorsolateral prefrontal cortex bulk RNA-seq data, then used the RNA-seq deconvolution algorithm CIBERSORTx to generate SCZ brain single-cell RNA-seq data for a comprehensive analy...

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Literature Corpus work: 3c0c9480-d3dd-5f4a-bb95-8b4ce11e8ad5
DOI: 10.20944/preprints202208.0341.v1

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