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METTL3-Mediated m6A mRNA Modification of FBXW7 Suppresses Lung Adenocarcinoma

2020-10-13

Abstract excerpt

<h4>Background: </h4> FBXW7 m 6 A modification plays an important role in lung adenocarcinoma (LUAD) progression; however, the underlying mechanisms remain unclear.MethodsThe correlation between FBXW7 and various genes related to m 6 A modification was analyzed using The Cancer Genome Atlas database. The regulatory effects of METTL3 on FBXW7 mRNA m 6 A modification were examined in a cell model, and the underlying...

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Literature Corpus work
c6a6fa35-5926-5b3c-b413-0a92189b453b
DOI
10.21203/rs.3.rs-90362/v1
Open publication

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METTL3-Mediated m6A mRNA Modification of FBXW7 Suppresses Lung AdenocarcinomaDOI 10.21203/rs.3.rs-90362/v1
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