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Article

Epigenetic Regulation of m6A Modifications in Human Cancer

28 Nov 2019

Abstract excerpt

N6-methyladenosine (m 6 A) is the most prevalent internal RNA modification, especially within eukaryotic messenger RNAs (mRNAs). m 6 A modifications of RNA regulate splicing, translocation, stability, and translation into proteins. m 6 A modifications are catalyzed by RNA methyltransferases, such as METTL3, METTL14, and WTAP (writers); the modifications are removed by the demethylases fat mass and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 31887551
DOI: 10.1016/j.omtn.2019.11.022

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