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Article

N6-methyladenosine modification of ITGA6 mRNA promotes the development and progression of bladder cancer

10 Aug 2019

Abstract excerpt

Background Accumulating evidence has revealed the critical roles of N 6 -methyladenosine (m 6 A) modification of mRNA in various cancers. However, the biological function and regulation of m 6 A in bladder cancer (BC) are not yet fully understood. Methods We performed cell phenotype analysis and established in vivo mouse xenograft models to assess the effects of m 6 A-modified ITGA6 on BC growth and progression....

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PMID: 31409574
DOI: 10.1016/j.ebiom.2019.07.068

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