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GRPa-PRS: A risk stratification method to identify genetically-regulated pathways in polygenic diseases

2023-06-27

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Polygenic risk scores (PRS) are tools used to evaluate an individual’s susceptibility to polygenic diseases based on their genetic profile. A considerable proportion of people carry a high genetic risk but evade the disease. On the other hand, some individuals with a low risk of eventually developing the disease. We hypothesized that unknown counterfactors might be involved in...

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Literature Corpus work
c68eed8c-978a-5983-b714-b696063d2d75
DOI
10.1101/2023.06.19.23291621
Open publication

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GRPa-PRS: A risk stratification method to identify genetically-regulated pathways in polygenic diseasesDOI 10.1101/2023.06.19.23291621
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