Article

Development and Characterization of Patient-Derived Xenografts from Non-Small Cell Lung Cancer Brain Metastases

2020-06-03

Abstract excerpt

<h4>Introduction</h4> The purpose of this study was to establish and characterize a direct-from patient-derived xenograft (PDX) model of non-small cell lung cancer (NSCLC) brain metastases. <h4>Methods</h4> Surgically obtained tissue was implanted subcutaneously and as orthotopic intracranial implants into immunodeficient mice. Histology and DNA loci were compared between original tumor and subsequent PDX passag...

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Literature Corpus work: c64a8f2f-3edb-5b5d-be14-302be6e3ef5b
DOI: 10.1101/2020.06.02.130062

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