Article

Patient-derived xenograft models of human non-small cell lung cancer: pre-clinical and clinical factors for consideration

2023-03-10

Abstract excerpt

<title>Abstract</title> <p>Despite the widespread utilization of Patient-Derived Xenografts (PDXs) as preclinical platforms in lung cancer research, there are concerns regarding their capability to accurately represent the tumor's clinical and molecular features across sequential passages. In this study, we established a Non-Small Cell Lung Cancer (NSCLC) PDX model in NSG-SGM3 mice and assessed clinical and precl...

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Literature Corpus work: 3f90417f-2274-548b-9c96-84e777ecaa35
DOI: 10.21203/rs.3.rs-2569321/v1

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