Article
Establishment and Characterization of a Pair of Patient-derived Human Non-small Cell Lung Cancer Cell Lines from a Primary Tumor and Corresponding Lymph Node Metastasis.
Anticancer research - 1 Apr 2016
Gebauer Florian, Wicklein Daniel, Tachezy Michael, Grob Tobias, Steinemann Doris, Manukjan Georgi, Göhring Gudrun, Schlegelberger Brigitte, Maar Hanna, Izbicki Jakob R, Bockhorn Maximilian, Schumacher Udo
Abstract excerpt
BACKGROUND: Non-small lung cancer is the leading cause of cancer-related mortality worldwide. For a deeper understanding of tumor biology, we established a pair of cell lines derived from a primary tumor and a corresponding lymph node metastasis. MATERIAL AND METHODS: The cell line BC4323 from the primary tumor (PT) and a mediastinal lymph node metastasis (LN) were derived from an adenocarcinoma (pT2, pN2, G3,...
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