Article

Spatiotemporal regulation of the hepatocyte growth factor receptor MET activity by sorting nexins 1/2 in HCT116 colorectal cancer cells

2024-02-12

Abstract excerpt

<h4>ABSTRACT</h4> Cumulative research findings support the idea that endocytic trafficking is crucial in regulating receptor signaling and associated diseases. Specifically, strong evidence points to the involvement of sorting nexins (SNXs), particularly SNX1 and SNX2, in the signaling and trafficking of the receptor tyrosine kinase (RTK) MET in colorectal cancer (CRC). Activation of hepatocyte growth factor (HGF...

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Literature Corpus work: c61670da-8d3c-5543-82c9-bf49abeca0ea
DOI: 10.1101/2024.02.10.579658

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