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Article

Inhibitory regulation of EGF receptor degradation by sorting nexin 5.

Biochemical and biophysical research communications - 7 Apr 2006

Liu Hao, Liu Zu-Qiang, Chen Carol X-Q, Magill Stephen, Jiang Yu, Liu Yong-Jian

Abstract excerpt

Endosomal trafficking of EGF receptor (EGFR) upon stimulation is a highly regulated process during receptor-mediated signaling. Recently, the sorting nexin (SNX) family has emerged as an important regulator in the membrane trafficking of EGFR. Here, we report the identification of a novel interaction between two members of the family, SNX1 and SNX5, which is mediated by the newly defined BAR domain of both SNXs....

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Identifiers

PMID: 16487940
DOI: 10.1016/j.bbrc.2006.01.179

Genes

SNX5
EGFR
SNX1
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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