Article
The Sarcomeric M-Region: A Molecular Command Center for Diverse Cellular Processes
1 Jan 2015
Abstract excerpt
The sarcomeric M-region anchors thick filaments and withstands the mechanical stress of contractions by deformation, thus enabling distribution of physiological forces along the length of thick filaments. While the role of the M-region in supporting myofibrillar structure and contractility is well established, its role in mediating additional cellular processes has only recently started to emerge. As such,...
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