Article

Thick Filament Protein Network, Functions, and Disease Association

2018-04-01

Abstract excerpt

ABSTRACT Sarcomeres consist of highly ordered arrays of thick myosin and thin actin filaments along with accessory proteins. Thick filaments occupy the center of sarcomeres where they partially overlap with thin filaments. The sliding of thick filaments past thin filaments is a highly regulated process that occurs in an ATP‐dependent manner driving muscle contraction. In addition to myosin that makes up the backbo...

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Literature Corpus work: 9b01b9e5-26ac-5b60-b6f2-50536bb7057b
DOI: 10.1002/j.2040-4603.2018.tb00019.x

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