Article

SCENIC: Single-cell regulatory network inference and clustering

2017-05-31

Abstract excerpt

Single-cell RNA-seq allows building cell atlases of any given tissue and infer the dynamics of cellular state transitions during developmental or disease trajectories. Both the maintenance and transitions of cell states are encoded by regulatory programs in the genome sequence. However, this regulatory code has not yet been exploited to guide the identification of cellular states from single-cell RNA-seq data. Her...

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Literature Corpus work: c31e6414-df5c-5f0a-9ad0-d3ac75f99424
DOI: 10.1101/144501

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