Article
An extensive enhancer-promoter map generated by genome-scale analysis of enhancer and gene activity patterns
2017-09-18
Abstract excerpt
Massive efforts have documented hundreds of thousands of putative enhancers in the human genome. A pressing genomic challenge is to identify which of these enhancers are functional and map them to the genes they regulate. We developed a novel method for inferring enhancer-promoter (E-P) links based on correlated activity patterns across many samples. Our method, called FOCS , uses rigorous statistical validation...
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Identifiers and source
- Literature Corpus work
- 4c3f71be-07d5-51d5-89d5-46190c25de78
- DOI
- 10.1101/190231
