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A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes

2021-01-29

Abstract excerpt

<h4>Purpose</h4> A subset of primary prostate cancer (PCa) expresses programmed death-ligand 1 (PD-L1), but whether they have unique tumor immune microenvironment (TIME) or genomic features is unclear. <h4>Experimental Design</h4> We selected PD-L1-positive high-grade and/or high-risk primary PCa, characterized tumor-infiltrating lymphocytes (TILS) with multiplex immunofluorescence, and identified genomic alterati...

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Literature Corpus work
c52f204a-05ad-5551-8164-9b7dbe3eb353
DOI
10.1101/2021.01.27.21250464
Open publication

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A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor GenesDOI 10.1101/2021.01.27.21250464
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