Article

Tumor Immune Microenvironment Clusters in Localized Prostate Adenocarcinoma: Prognostic Impact of Macrophage Enriched/Plasma Cell Non-enriched Subtypes

2020-05-28

Abstract excerpt

<h4>Background: </h4> Prostate cancer (PCa) is characterized by significant heterogeneity in its molecular, genomic, and immunologic characteristics. <h4>Methods:</h4> Whole transcriptome RNAseq data from The Cancer Genome Atlas of prostate adenocarcinomas (n=496) was utilized. The immune microenvironment was characterized using the CIBERSORTX tool to identify immune cell type composition. Unsupervised hierarchica...

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Literature Corpus work: 24aa51e6-de7f-54c2-81d3-d1430c138962
DOI: 10.20944/preprints202005.0462.v1

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