Back to search

Article

Integrated single-cell and spatial transcriptomic analyses unravel the heterogeneity of the prostate tumor microenvironment

2022-03-19

Abstract excerpt

<h4>Summary</h4> The treatment of primary prostate cancer delicately balances an active surveillance approach for low-risk disease with multimodal treatment including surgery, radiation therapy, and hormonal therapy for high-risk disease. Recurrence and development of metastatic disease remains a clinical problem, without a clear understanding of what drives immune escape and tumor progression. Here, we sought to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
71dd2e27-935d-54b6-b637-30f43586c117
DOI
10.1101/2022.03.18.484781
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Integrated single-cell and spatial transcriptomic analyses unravel the heterogeneity of the prostate tumor microenvironmentDOI 10.1101/2022.03.18.484781
Select a neighboring publication to make it the new centre.