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Vrc01-class Precursor Frequency in an African Population is Influenced by Ighv1-2 Allelic Composition and Not Malaria Exposure

2026-06-24

Abstract excerpt

<title>Abstract</title> <p>Recent innovations in vaccine design have reignited optimism about the feasibility of developing a safe and effective HIV vaccine. For instance, germline-targeting (GT) immunogens have been designed to selectively expand naïve B cell precursors with broadly neutraliing antibodies (bnAbs)-associated germline-encoded features, thereby priming them for structure-guided maturation. The freq...

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Literature Corpus work
c4945a83-c9e6-5556-8fba-3ad5142a9358
DOI
10.21203/rs.3.rs-9732671/v1
Open publication

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Vrc01-class Precursor Frequency in an African Population is Influenced by Ighv1-2 Allelic Composition and Not Malaria ExposureDOI 10.21203/rs.3.rs-9732671/v1
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