Article

Vaccine genetics of IGHV1-2 VRC01-class broadly neutralizing antibody precursor naïve human B cells

2021-03-02

Abstract excerpt

<h4>ABSTRACT</h4> A successful HIV vaccine must overcome the hurdle of being able to activate naïve precursor B cells encoding features within their germline B cell receptors (BCR) that allow recognition of broadly neutralizing epitopes. Knowledge of whether broadly neutralizing antibody (bnAb) precursor B cells are circulating at sufficient frequencies within individuals in communities heavily impacted by HIV ma...

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Literature Corpus work: f0db293a-8e98-529d-874c-722479343e6d
DOI: 10.1101/2021.03.01.433480

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