Article

Regulation of synaptic connectivity in schizophrenia by mutual neuron-microglia interaction

2022-07-13

Abstract excerpt

<title>Abstract</title> <p>The examination of post-mortem brain tissue suggests synaptic loss as a central pathological hallmark of schizophrenia. Synaptic loss has been shown to be related to increased inflammation in the central nervous system. Aberrant activation of microglia, the immune cells of the human brain, may account for neuronal damage in schizophrenia. Induced pluripotent stem cells represent a promi...

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Literature Corpus work: c462c7dc-566f-5368-8bda-d3dd25ed9ec8
DOI: 10.21203/rs.3.rs-1792046/v1

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