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Identification of neuron-glia signaling feedback in human schizophrenia using patient-derived, mix-and-match forebrain assembloids

2024-12-23

Abstract excerpt

Although abnormal activities across multiple cell types are believed to contribute to the development of various neurodevelopmental disorders, current brain organoid technologies fall short in accurately modeling the dynamic cellular interactions in the human brain. Recently, we developed a cellular reconstitution technology to create human forebrain assembloids with enhanced cellular diversity, representing dynam...

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Identifiers and source

Literature Corpus work
e06296fa-404d-5548-b864-55a4d837a078
DOI
10.1101/2024.12.22.629557
Open publication

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Identification of neuron-glia signaling feedback in human schizophrenia using patient-derived, mix-and-match forebrain assembloidsDOI 10.1101/2024.12.22.629557
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