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Biogenesis of cytochromes <i>c</i> and <i>c</i> <sub>1</sub> in the electron transport chain of malaria parasites

2024-02-01

Abstract excerpt

<h4>ABSTRACT</h4> Plasmodium malaria parasites retain an essential mitochondrional electron transport chain (ETC) that is critical for growth within humans and mosquitoes and a key antimalarial drug target. ETC function requires cytochromes c and c 1 that are unusual among heme proteins due to their covalent binding to heme via conserved CXXCH sequence motifs. Heme attachment to these proteins in most eukaryote...

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Literature Corpus work
c40f97d4-3a65-5a0b-a781-e8d164609516
DOI
10.1101/2024.02.01.575742
Open publication

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Biogenesis of cytochromes <i>c</i> and <i>c</i> <sub>1</sub> in the electron transport chain of malaria parasitesDOI 10.1101/2024.02.01.575742
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