Article

A mutagenesis screen for essential plastid biogenesis genes in human malaria parasites

2018-08-27

Abstract excerpt

<h4>Summary</h4> Endosymbiosis has driven major molecular and cellular innovations. Plasmodium spp. parasites that cause malaria contain an essential, non-photosynthetic plastid, the apicoplast, which originated from a secondary (eukaryote-eukaryote) endosymbiosis. To discover organellar pathways with evolutionary and biomedical significance, we performed a mutagenesis screen for essential genes required for api...

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Literature Corpus work: 3b18a3e9-8634-5cf8-9364-359d5779075d
DOI: 10.1101/401570

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