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Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in <i>Plasmodium berghei</i>

2024-10-14

Abstract excerpt

Malaria is caused by protozoan parasites of the genus Plasmodium and remains a global health concern. The parasite has a highly adaptable life cycle comprising successive rounds of asexual replication in a vertebrate host and sexual maturation in the mosquito vector Anopheles . Genetic manipulation of the parasite has been instrumental for deciphering the function of Plasmodium genes. Conventional reverse genet...

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Literature Corpus work
ef9000aa-8783-5d07-9e19-33a8f1ba8f16
DOI
10.1101/2024.10.14.618196
Open publication

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Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in <i>Plasmodium berghei</i>DOI 10.1101/2024.10.14.618196
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